We aim to boost the already existing defence mechanism against stress, by which we can allow your brain cells to repair myelin. We think that it is possible to delay or even stop the progression of the disease with this method.

Myelin is a fatty structure that insulates your nerve cells. Myelin is important for both transmitting the signal in your nerves and protecting that same nerve. When multiple sclerosis progresses, the cells that make myelin die. The body can reproduce these cells again by utilising precursor cells. These cells are present in large numbers, including in people with MS. But unfortunately, these cells no longer execute their repair function. We want to ensure that these cells can execute their function again. But living with MS means that there is a lot of stress present in your brain, called oxidative stress. These are molecules that occur more often in MS patients. The precursor cells that should provide repair are extra vulnerable to this stress. This consumes all their energy, leaving nothing to perform their function. We are investigating how we can boost the already existing defence mechanism against stress and thereby give the cells the opportunity to repair myelin.